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New aureolic acid antibiotics. I. Screening, isolation, characterization and biological properties
M Koenuma1, N Uchida, K Yamaguchi
1Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
The Journal of Antibiotics
|January 1, 1988
Abstract:
A new antibiotic complex was isolated from the fermentation broth of Streptomyces aburaviensis PA-39856. The individual factors, demethylolivomycins A, B and demethylchromomycins A2, A3 were separated and purified by preparative HLC. These antibiotics possess high activities against Gram-positive bacteria and P388 leukemia in mice.