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Reduced heart-rate variability and increased risk of hypertension-a prospective study of the ELSA-Brasil
Rosangela A Hoshi1, Itamar S Santos2, Eduardo M Dantas3
1Center for Clinical and Epidemiological Research of the University Hospital, University of Sao Paulo, São Paulo, São Paulo, Brazil. rosangela.hoshi@gmail.com.
Abstract:
Although autonomic disturbances are known to precede hypertension onset, the risks underlying different ranges of blood pressure and impaired cardiac autonomic modulation are still unknown. This study aimed to identify the risk of hypertension incidence related to low heart-rate variability profile in normotensive blood pressure subcategories: normal (<120/80 mmHg) and prehypertension (120/80-139/89 mmHg) in a 4-year follow-up. 7665 participants free of hypertension at baseline were examined. They were allocated into one of two groups (
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