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Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
Published on: October 29, 2015
Traditional foods with their constituent's antiviral and immune system modulating properties
Md Mahbubur Rahman1, Ashik Mosaddik2, Ahm Khurshid Alam2
1Department of Pharmacy, Varendra University, Rajshahi, 6204, Bangladesh.
Background:
Viruses are responsible for several diseases, including severe acute respiratory syndrome, a condition caused by today's pandemic coronavirus disease (COVID-19). A negotiated immune system is a common risk factor for all viral infections, including COVID-19. To date, no specific therapies or vaccines have been approved for coronavirus. In these circumstances, antiviral and immune boosting foods may ensure protection against viral infections, especially SARS-CoV-2 by reducing risk and ensuring fast healing of SARS-CoV-2 illness.
Scope And Approach:
In this review, we have conducted an online search using several search engines (Google Scholar, PubMed, Web of Science and Science Direct) to find out some traditional foods (plant, animal and fungi species), which have antiviral and immune-boosting properties against numerous viral infections, particularly coronaviruses (CoVs) and others RNA-virus infections. Our review indicated some foods to be considered as potential immune enhancers, which may help individuals to overcome viral infections like COVID-19 by modulating immune systems and reducing respiratory problems. Furthermore, this review will provide information regarding biological properties of conventional foods and their ingredients to uphold general health.
Key Findings And Conclusions:
We observed some foods with antiviral and immune-boosting properties, which possess bioactive compounds that showed significant antiviral properties against different viruses, particularly RNA viruses such as CoVs. Interestingly, some antiviral and immune-boosting mechanisms were very much similar to the antiviral drug of COVID-19 homologous SARS (Severe Acute Respiratory Syndrome Coronavirus) and MERS (Middle East Respiratory Syndrome Coronavirus). The transient nature and the devastating spreading capability of COVID-19 lead to ineffectiveness of many curative therapies. Therefore, body shielding and immune-modulating foods, which have previous scientific recognition, have been discussed in this review to discern the efficacy of these foods against viral infections, especially SARS-CoV-2.
Insights
Certain foods possess antiviral and immune-boosting properties beneficial for combating viral infections like COVID-19. These natural compounds may help modulate the immune system and reduce respiratory issues, offering a protective approach against coronaviruses.
Area of Science:
- Food Science
- Virology
- Immunology
Background:
- Coronaviruses, including SARS-CoV-2, cause significant global health issues like COVID-19.
- Compromised immune systems increase susceptibility to viral infections.
- Limited specific therapies and vaccines necessitate alternative protective strategies.
Purpose of the Study:
- To identify traditional foods with antiviral and immune-boosting properties.
- To explore the potential of these foods against viral infections, particularly coronaviruses.
- To provide information on the biological properties of foods for general health and immune support.
Main Methods:
- Comprehensive online literature search using major scientific databases (PubMed, Web of Science, Google Scholar, Science Direct).
- Review of traditional food sources, including plant, animal, and fungal species.
- Analysis of scientific literature on bioactive compounds and their antiviral mechanisms.
Main Results:
- Several foods exhibit significant antiviral properties against RNA viruses, including coronaviruses.
- Bioactive compounds in these foods demonstrate mechanisms similar to known antiviral drugs for SARS and MERS.
- Identified foods can act as immune enhancers, potentially aiding recovery from viral illnesses.
Conclusions:
- Antiviral and immune-modulating foods offer a promising complementary approach to managing viral infections like COVID-19.
- Dietary interventions with scientifically recognized foods can support immune function and potentially mitigate disease severity.
- Further research into the efficacy of specific food-derived compounds against SARS-CoV-2 is warranted.
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