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Nanotechnology in neurosurgery: a systematic review
Dimitrios Giakoumettis1,2, Spyros Sgouros3,4
1Department of Neurosurgery, "Evangelismos" Hospital, Athens, Greece.
Summary
Nanotechnology offers advanced diagnosis and treatment for neurological conditions. This review highlights key advances in neurosurgery, paving the way for future clinical applications in neuroimaging and neuro-nanotherapy.
Area of Science:
- Interdisciplinary medical science
- Nanotechnology and nanomedicine
- Neurosurgery applications
Background:
- Nanotechnology is revolutionizing medical diagnosis, treatment, and monitoring.
- This review focuses on nanotechnology's role in advancing neurosurgery.
Purpose of the Study:
- To systematically review and summarize advancements in nanotechnology for neurosurgery.
- To identify key areas of application and future potential.
Main Methods:
- PubMed advanced search adhering to PRISMA guidelines.
- Review of original studies from the last decade.
- Data extraction included study details, nanomedical materials, and neurosurgical fields.
Main Results:
- 78 original studies were included, categorized by neurosurgical and nanomedical fields.
- Applications span functional neurosurgery, neuro-oncology, neurodegenerative diseases, and more.
- Key nanomedical fields include neuroimaging, neuro-nanotechnology, neuroregeneration, theranostics, and neuro-nanotherapy.
Conclusions:
- Significant progress in central nervous system disease imaging and treatment is evident.
- Nanotechnology techniques are rapidly evolving.
- Clinical integration of these advances is anticipated within the next decade.

