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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Pediatric keratoconus - Current perspectives and clinical challenges
Venugopal Anitha1, Murugesan Vanathi2, Anita Raghavan3
1Cornea Consultant, Aravind Eye Hospital & Postgraduate Institute, Tirunelveli, Tamil Nadu, India.
Insights
Pediatric keratoconus, an aggressive eye condition, requires early diagnosis and collagen crosslinking to prevent vision loss. Management differs from adults due to faster progression and associated health issues in children.
Area of Science:
- Ophthalmology
- Corneal diseases
- Pediatric eye care
Background:
- Keratoconus is a progressive ectatic corneal disease causing vision impairment.
- Pediatric keratoconus presents unique challenges due to accelerated progression and co-morbidities.
- This condition significantly impacts children's quality of life, social integration, and education.
Purpose of the Study:
- To discuss the epidemiology and etiopathogenesis of pediatric keratoconus.
- To highlight the clinical challenges in diagnosing and managing pediatric keratoconus.
- To review current management strategies and perspectives for pediatric keratoconus.
Main Methods:
- Review of existing literature on pediatric keratoconus.
- Analysis of epidemiological data and disease progression patterns.
- Evaluation of current treatment modalities and their outcomes.
Main Results:
- Pediatric keratoconus is more aggressive than adult forms, necessitating distinct management approaches.
- Early detection and collagen crosslinking are crucial for arresting disease progression.
- Associated ocular conditions, like severe allergic conjunctivitis, complicate treatment and management.
Conclusions:
- Timely intervention with collagen crosslinking is vital for preserving vision in pediatric keratoconus.
- Comprehensive management considering co-morbidities and patient compliance is essential.
- While keratoplasty offers good outcomes, managing post-operative complications requires attention.
Abstract:
Keratoconus is an ectatic corneal disease characterized by progressive stromal thinning, irregular astigmatism, and defective vision. It can be unilateral or bilateral with asymmetric presentation. It starts at puberty and either progresses rapidly to an advanced stage of the disease or stops in case of delayed onset and slow progression. Pediatric keratoconus is more aggressive than in adults and the management protocols differ because of various rationales such as accelerated progression, advanced stage of disease at the time of diagnosis and co-morbidities. It poses a burden to the society as it affects the quality of life, social, and educational development in children. Hence early diagnosis, recognition of progression, and timely intervention with collagen crosslinking is imperative to arrest the worsening. Association with systemic syndromes and ocular comorbidities can be of concern in pediatric keratoconus. Severe ocular allergy when associated hastens progress and complicates timely intervention of crosslinking treatment and compliance to contact lens wear. Keratoplasty in pediatric keratoconus has good outcomes but can encounter frequent suture-related concerns. This article discusses the epidemiology, etiopathogenesis, clinical challenges, and current perspectives of management of pediatric keratoconus.
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