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Updated: Nov 20, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Updates in the evidence-based management of cutaneous melanoma
Ryan P Goepfert1, Jeffrey N Myers1, Jeffrey E Gershenwald2
1Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Abstract:
Treatment of cutaneous melanoma is changing with significant developments over the past several years that promise to reshape the field of melanoma surgical oncology. Modifications to the staging system based on analysis of a large international dataset, the timing and extent of regional lymphadenectomy, the emergence of effective systemic therapies in the neoadjuvant and adjuvant setting, and the role of adjuvant radiation are all undergoing a data-driven evolution. Surgeon engagement in multidisciplinary decision making remains an essential component of contemporary management for patients across all stages of melanoma and demands specific involvement of head and neck surgical oncologists.
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