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Using Solution Electrowriting to Control the Properties of Tubular Fibrous Conduits.

Anthony R D'Amato¹, Xiaochu Ding¹, Yadong Wang¹

¹Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, 134 Hollister Drive, 283 Kimball Hall, Ithaca, New York 14853-0001, United States.

ACS Biomaterials Science & Engineering

|January 19, 2021

Summary

Solution electrowriting enables tunable fibrous conduits with controlled patterns and porosity. Solvent properties are key to tailoring scaffold architecture, offering advanced customization beyond traditional electrospinning.

Keywords:

additive manufacturing electrospinning electrostatic writing material fabrication scaffold vascular graft

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Area of Science:

Materials Science
Biomaterials Engineering
Additive Manufacturing

Background:

Advanced additive manufacturing techniques offer tunable properties and architecture.
Traditional solution electrospinning has limitations in pattern resolution and tunability.
Newer methods provide enhanced control over scaffold design.

Purpose of the Study:

To present solution electrowriting as a method for creating tunable fibrous conduits.
To demonstrate the impact of solvent selection on scaffold structure.
To highlight the versatility and control offered by solution electrowriting.

Main Methods:

Utilized solution electrowriting to fabricate fibrous conduits from various polymers.
Investigated the role of solvent polarity and volatility in controlling scaffold morphology.
Adapted conventional electrospinning equipment for electrowriting.

Main Results:

Achieved tunable patterns, dimensions, and scaffold porosity.
Demonstrated precise control over scaffold structure by manipulating solvent properties.
Showcased the ability to produce customized fibrous materials.

Conclusions:

Solution electrowriting is a versatile technique for fabricating customized fibrous scaffolds.
Solvent selection is a critical parameter for controlling scaffold architecture in electrowriting.
This method offers enhanced control and customization compared to conventional solution electrospinning.