Related Experiment Video
Updated: Nov 20, 2025
09:31
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
9.1K
Virtual Unenhanced Dual-Energy CT Images Obtained with a Multimaterial Decomposition Algorithm: Diagnostic Value for
Jennifer M Xiao1, Daniel S Hippe1, Mladen Zecevic1
1From the Department of Radiology, University of Washington School of Medicine, Box 357115, 1959 NE Pacific St, Seattle, WA 98195 (J.M.X., D.S.H., M.Z., D.A.Z., L.M.C., G.V.T., M.K.D., R.B.O., W.P.S., C.L.W., A.M.); and Global Research Organization, GE Healthcare, Houston, Tex (A.G.C.).
Radiology
|January 19, 2021
Summary
Virtual unenhanced (VUE) CT images show promise for abdominal diagnostics, maintaining renal mass classification accuracy. However, VUE images demonstrate suboptimal performance for detecting small urinary stones compared to true unenhanced (TUE) images.
Area of Science:
- Radiology
- Medical Imaging
- Dual-Energy CT
Background:
- Virtual unenhanced (VUE) images from dual-energy CT (DECT) multimaterial decomposition algorithms offer potential for abdominal diagnostics.
- These VUE images are being evaluated as a substitute for true unenhanced (TUE) images.
Purpose of the Study:
- To assess the diagnostic utility of VUE images generated by a DECT multimaterial decomposition algorithm.
- The study focused on patients undergoing evaluation for renal masses and urinary stones.
Main Methods:
- A retrospective analysis compared VUE and TUE images quantitatively and qualitatively.
- Four radiologists assessed image quality and diagnostic performance.
- Statistical analysis included limits of agreement for attenuation differences and receiver operating characteristic curves for stone detection.
Main Results:
- Renal mass attenuation differences between VUE and TUE images were minimal (within 3 HU).
- Classification of renal masses (enhancing vs. non-enhancing cysts) remained unchanged.
- VUE images showed lower diagnostic performance for urinary stone detection compared to TUE images, particularly for stones ≤3 mm.
Conclusions:
- VUE images are unlikely to alter renal mass classification accuracy.
- The diagnostic performance of VUE images for detecting small urinary stones remains suboptimal.
Related Concept Videos
01:27Imaging Studies III: Computed Tomography
129
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
129
01:24Imaging Studies II: Ultrasonography
141
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
141
01:30Urinary Tract Calculi III: Medical Management
85
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
85
01:28Imaging Studies I: Kidney, Ureter, and Bladder Studies
107
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
107
01:22Imaging Studies V: Intravenous Urography and Retrograde Pyelography
553
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
553
01:27Imaging Studies IV: Magnetic Resonance Imaging
124
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
124