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Cryptococcus bacillisporus (VGIII) Meningoencephalitis Acquired in Santa Cruz, Bolivia

Luis Thompson1, Lorena Porte2, Violeta Díaz3

  • 1Unidad de Infectología, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7650568, Chile.

Journal of Fungi (Basel, Switzerland)
|January 20, 2021
PubMed

Insights

A rare fungal infection, chronic meningoencephalitis and hydrocephalus caused by Cryptococcus bacillisporus (VGIII), was identified in an immunocompetent patient. This finding confirms the presence of this emerging fungal pathogen in Bolivia, South America.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Neurology

Background:

  • The Cryptococcus gattii species complex comprises emerging fungal pathogens.
  • Geographical distribution and clinical presentations of Cryptococcus species are continually evolving.

Observation:

  • A case of chronic meningoencephalitis with hydrocephalus was diagnosed in an immunocompetent individual.
  • The causative agent was identified as Cryptococcus bacillisporus (VGIII).
  • The patient was from Santa Cruz, Bolivia.

Findings:

  • This report represents the first identification of a Cryptococcus gattii species complex member in Bolivia.
  • Cryptococcus bacillisporus (VGIII) is confirmed to be present in Bolivia's tropical regions.
  • The case expands the known geographical range of this fungal species.

Implications:

  • This finding enhances the epidemiological understanding of emerging fungal pathogens in South America.
  • Clinical awareness of Cryptococcus bacillisporus (VGIII) infections should be raised in this region.
  • Further research into the prevalence and clinical characteristics of this pathogen in South America is warranted.
Keywords:
Cryptococcus gattii complexSouth Americacryptococcosisepidemiologyfungal infections

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