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A Practical Guide to Metabolomics Software Development.

Hui-Yin Chang1,2, Sean M Colby3, Xiuxia Du4

  • 1Department of Pathology, University of Michigan, 1301 Catherine Street, Ann Arbor, Michigan 48109, United States.

Analytical Chemistry
|January 20, 2021
PubMed
Summary
This summary is machine-generated.

This perspective offers guidelines for developing impactful metabolomics software tools. It covers preparation, development, and distribution to aid researchers with varying programming expertise.

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Area of Science:

  • Metabolomics
  • Bioinformatics
  • Scientific Software Development

Background:

  • Numerous software tools are available for metabolomics data processing and analysis.
  • Tools are often developed by practitioners with limited software engineering experience.
  • Users of these tools possess a wide range of technical skills, from basic data analysis to advanced programming.

Purpose of the Study:

  • To provide essential considerations for maximizing the impact of publicly available metabolomics software tools.
  • To offer best practices for metabolomics tool development.
  • To guide both metabolomics software users and developers.

Main Methods:

  • The recommendations are based on the collective experience of a working group from the NIH-sponsored Metabolomics Consortium.
  • The guidelines are structured into three key stages: preparation, tool development, and distribution and maintenance.
  • The perspective is aimed at metabolomics researchers, including those with limited formal programming backgrounds.

Main Results:

  • The perspective outlines critical factors influencing the success and adoption of metabolomics software.
  • It provides a framework for developing user-friendly and robust metabolomics tools.
  • The recommendations address the entire lifecycle of a software tool, from conception to ongoing support.

Conclusions:

  • Adhering to best practices in software development can significantly enhance the utility and impact of metabolomics tools.
  • Clear guidelines are needed to support researchers in creating and utilizing metabolomics software effectively.
  • Collaboration and shared knowledge are crucial for advancing the field of metabolomics through improved software resources.