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Updated: Nov 20, 2025

An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
[Resected Metachronous Pancreatic Metastasis from Rectal Cancer-A Case Report]
Koji Numata1, Nozomi Urata, Yuta Nakayama
1Dept. of Surgery, Hiratsuka Kyosai Hospital.
Abstract:
A 68-year-old woman had undergone laparoscopic high anterior resection for rectal cancer. Two years postoperatively, metachronal pulmonary metastases and cerebellar metastasis were surgically resected. Three and a half years after the primary surgery, computed tomography(CT)demonstrated a nodule at the pancreatic tail. Under suspected primary pancreatic cancer or metastasis from rectal cancer, we performed distal pancreatectomy. Histological examination of the pancreatic tumor suggested a metastasis from the rectal cancer since tumor cells were negative for CK7 and positive for CK20 and CDX2 immunohistochemically. Three months after the pancreatic resection, CT demonstrated hepatic and cerebellar metastases. After subsequent chemotherapy, liver metastasis disappeared. The cerebellar metastasis shrank with radiotherapy.
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