Related Experiment Video
Updated: Nov 20, 2025

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
[Local Recurrence of Breast Cancer Eight Years after Mastectomy-A Case Report]
Keita Adachi1, Shuhei Suzuki, Tomohiro Hirano
1Dept. of Surgery, The Nippon Dental University School of Life Dentistry.
Abstract:
A 68-year-old woman had undergone mastectomy for right breast cancer when she was 60 years of age. The histopathological diagnosis had been scirrhous carcinoma, T1N0M0, stage Ⅰ. She had received anastrozole as the adjuvant therapy for 5 years. Eight years after the operation, she consulted our department because of a lump on the right chest wall. The metastatic work-up revealed no evidence of metastases. Tumorectomy was performed. Histopathological findings from the surgically resected specimens showed scirrhous carcinoma, positive for ER and PgR, and negative for HER2/neu protein expression. The Ki-67 positive cell index was 25%. Therefore, we diagnosed the patient with local recurrence of breast cancer. Since surgical margins were positive, irradiation was performed at the recurrence site, and letrozole was administered. Local recurrence is a target of the curative treatment and requires a multidisciplinary approach, including surgery, drugs, and radiation therapy. We report a case of local recurrence of breast cancer 8 years after mastectomy.

