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Design and Fabrication of an Elastomeric Unit for Soft Modular Robots in Minimally Invasive Surgery

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Multi-functionalized micro-helical capsule robots with superior loading and releasing capabilities.

Yanting Liu¹, Yuanyuan Yang², Xiong Yang²

¹Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China. wf.shang@siat.ac.cn and Department of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077 SAR, People's Republic of China.

Journal of Materials Chemistry. B

|January 20, 2021

Summary

This summary is machine-generated.

Researchers developed a multifunctional magnetic micro-helical robot for targeted cargo delivery. This microrobot offers enhanced locomotion and controlled release of encapsulated materials, addressing key challenges in biomedical applications.

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Area of Science:

Biomedical Engineering
Materials Science
Robotics

Background:

Microrobot functionalization is crucial for biomedical applications like targeted drug delivery.
Integrating multifunctionality and controllable cargo release in microrobots presents significant challenges.

Purpose of the Study:

To develop a multifunctional micro-helical robot with enhanced loading and controlled release capabilities.
To address the limitations in current microrobot technology for biomedical cargo delivery.

Main Methods:

Fabrication of a micro-helical robot using microfluidic synthesis, polyelectrolyte complexation, and magnetic nanoparticle coating.
Utilizing a co-axial capillary microfluidic system for calcium alginate microfiber construction.
Employing multi-step layer-by-layer assembly to create a functionalized alginate/chitosan/alginate shell with Fe3O4 nanoparticles.

Main Results:

The developed microrobot exhibits wireless steering and rotational locomotion controlled by a six degrees of freedom (6-DOFs) electromagnetic system.
The microrobot demonstrates stimuli-responsive, controllable release of encapsulated materials triggered by environmental ions.
The helical capsule structure provides superior loading capacity and biocompatibility.

Conclusions:

This work presents an efficient strategy for multi-functionalizing microrobots.
The developed microrobots show enhanced locomotion and encapsulation performance for cargo loading, transport, and targeted delivery.
The study advances microrobot capabilities for complex biomedical tasks.