Related Experiment Video
Updated: Nov 20, 2025

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
Clinical Outcomes of Critically III Patients with COVID-19 by Race
Fahad Marmarchi1, Michael Liu1, Srikant Rangaraju1
1Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Insights
African Americans with COVID-19 had higher rates of comorbidities like hypertension and diabetes. Despite needing more renal replacement therapy, their intensive care unit outcomes and mortality were similar to other races.
Area of Science:
- Critical care medicine
- Infectious diseases
- Public health
Background:
- COVID-19 disproportionately affects African Americans.
- Understanding racial disparities in critical care for COVID-19 is essential.
- Comorbidities and clinical outcomes require examination across racial groups.
Purpose of the Study:
- To investigate comorbidities and clinical outcomes by race among intensive care unit (ICU) patients with COVID-19.
- To compare the severity of illness and treatment needs between African American and other racial groups admitted to the ICU.
Main Methods:
- A case series of critically ill COVID-19 patients admitted to an academic healthcare system in Atlanta, Georgia.
- Inclusion criteria: critically ill hospitalized patients between March 6, 2020, and May 5, 2020.
- Outcomes analyzed: mechanical ventilation, renal replacement therapy, and mortality, stratified by race.
Main Results:
- The study included 288 patients; 73% were African American.
- African Americans exhibited higher rates of hypertension, diabetes, and higher mean BMI.
- Despite increased need for renal replacement therapy in African Americans, intubation rates, ICU length of stay, and overall mortality were similar across racial groups.
Conclusions:
- Critically ill COVID-19 patients in this cohort were racially diverse.
- African Americans presented with more comorbidities but experienced similar mortality rates compared to other races.
- Findings highlight the complex interplay of race, comorbidities, and critical care outcomes in COVID-19.
Background:
Studies of COVID-19 have shown that African Americans have been affected by the virus at a higher rate compared to other races. This cohort study investigated comorbidities and clinical outcomes by race among COVID-19 patients admitted to the intensive care unit.
Methods:
This is a case series of critically ill patients admitted with COVID-19 to an academic healthcare system in Atlanta, Georgia. The study included all critically ill hospitalized patients between March 6, 2020, and May 5, 2020. Clinical outcomes during hospitalization included mechanical ventilation, renal replacement therapy, and mortality stratified by race.
Results:
Of 288 patients included (mean age, 63 ± 16 years; 45% female), 210 (73%) were African American. African Americans had significantly higher rates of comorbidities compared to other races, including hypertension (80% vs 59%, P = 0.001), diabetes (49% vs 34%, P = 0.026), and mean BMI (33 kg/m2 vs 28 kg/m2, P < 0.001). Despite African Americans requiring continuous renal replacement therapy during hospitalization at higher rates than other races (27% vs 13%, P = 0.011), rates of intubation, intensive care unit length of stay, and overall mortality (30% vs 24%, P = 0.307) were similar.
Conclusion:
This racially diverse series of critically ill COVID-19 patients shows that despite higher rates of comorbidities at hospital admission in African Americans compared with other races, there was no significant difference in mortality.
Related Concept Videos
Pneumonia III: Complications and Assessment
Acute Respiratory Failure-III
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-I
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Acute Coronary Syndrome IV: Interprofessional Care
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...

