Clinical Outcomes of Critically III Patients with COVID-19 by Race

Fahad Marmarchi1, Michael Liu1, Srikant Rangaraju1

  • 1Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.

Insights

African Americans with COVID-19 had higher rates of comorbidities like hypertension and diabetes. Despite needing more renal replacement therapy, their intensive care unit outcomes and mortality were similar to other races.

Area of Science:

  • Critical care medicine
  • Infectious diseases
  • Public health

Background:

  • COVID-19 disproportionately affects African Americans.
  • Understanding racial disparities in critical care for COVID-19 is essential.
  • Comorbidities and clinical outcomes require examination across racial groups.

Purpose of the Study:

  • To investigate comorbidities and clinical outcomes by race among intensive care unit (ICU) patients with COVID-19.
  • To compare the severity of illness and treatment needs between African American and other racial groups admitted to the ICU.

Main Methods:

  • A case series of critically ill COVID-19 patients admitted to an academic healthcare system in Atlanta, Georgia.
  • Inclusion criteria: critically ill hospitalized patients between March 6, 2020, and May 5, 2020.
  • Outcomes analyzed: mechanical ventilation, renal replacement therapy, and mortality, stratified by race.

Main Results:

  • The study included 288 patients; 73% were African American.
  • African Americans exhibited higher rates of hypertension, diabetes, and higher mean BMI.
  • Despite increased need for renal replacement therapy in African Americans, intubation rates, ICU length of stay, and overall mortality were similar across racial groups.

Conclusions:

  • Critically ill COVID-19 patients in this cohort were racially diverse.
  • African Americans presented with more comorbidities but experienced similar mortality rates compared to other races.
  • Findings highlight the complex interplay of race, comorbidities, and critical care outcomes in COVID-19.
Abstract

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