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Amniotic fluid lactate level as a diagnostic tool for prolonged labour.
Kinga Pospiech1, Krzysztof Czajkowski1
12nd Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.
Journal of Mother and Child
|January 20, 2021
Summary
Amniotic fluid lactate levels may predict prolonged labor. High levels suggest intervention, while low levels may allow for oxytocin augmentation, aiding clinical decisions in childbirth.
Area of Science:
- Obstetrics and Gynecology
- Biochemistry
- Perinatal Medicine
Background:
- Prolonged labor increases risks for mother and baby.
- Effective labor relies on progressive uterine contractions.
- Myometrial fatigue in prolonged labor shifts metabolism, increasing lactic acid.
Purpose of the Study:
- To review current knowledge on amniotic fluid lactate levels.
- To assess amniotic fluid lactate as a diagnostic tool for prolonged labor.
- To explore its role in guiding obstetric interventions.
Main Methods:
- Literature search of PubMed, EMBASE, Medline (1990-2020).
- Review of trials registers and reference lists.
- Focus on amniotic fluid lactate concentration in the first stage of labor.
Main Results:
- High amniotic fluid lactate is linked to ineffective contractions and labor arrest.
- Amniotic fluid lactate may predict the need for obstetric intervention.
- Low levels might support continuing vaginal labor with oxytocin.
Conclusions:
- Amniotic fluid lactate is a potential non-invasive marker for prolonged labor.
- Measuring lactate can aid in patient stratification for interventions like oxytocin.
- This could optimize management and improve maternal and fetal outcomes.
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