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Carbon nano-onions as potential nanocarriers for drug delivery

Michał Bartkowski1, Silvia Giordani1

  • 1School of Chemical Sciences, Dublin City University, Glasnevin, Ireland. silvia.giordani@dcu.ie.

Dalton Transactions (Cambridge, England : 2003)
|January 20, 2021
PubMed

Insights

Carbon nano-onions (CNOs) show promise as novel nanocarriers for drug delivery. This research explores their potential to overcome limitations of traditional drug delivery methods.

Area of Science:

  • Materials Science
  • Nanotechnology
  • Pharmaceutical Sciences

Background:

  • Nanocarriers offer targeted drug delivery, addressing issues like premature degradation and non-specific toxicity.
  • Existing nanocarrier systems have shown success, with some FDA-approved options available.
  • Limitations of free drug delivery include poor tissue penetration and multi-drug resistance.

Purpose of the Study:

  • To investigate the potential of carbon nano-onions (CNOs) as nanocarriers for drug delivery.
  • To outline criteria for nanocarrier design and assess CNOs against these standards.
  • To provide a foundational discussion on CNOs for drug delivery applications.

Main Methods:

  • Literature review and theoretical analysis of nanocarrier design principles.
  • Evaluation of carbon nano-onions (CNOs) based on established nanocarrier criteria.
  • Discussion of CNOs' properties relevant to drug encapsulation and release.

Main Results:

  • Carbon nano-onions (CNOs) possess characteristics suitable for nanocarrier applications.
  • CNOs align with key criteria for effective drug delivery systems.
  • The unique structure of CNOs suggests potential for targeted delivery and overcoming resistance.

Conclusions:

  • Carbon nano-onions (CNOs) represent a promising novel nanomaterial for drug delivery.
  • Further research into CNOs could lead to advanced therapeutic strategies.
  • CNOs offer a potential solution to current challenges in targeted drug delivery.

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