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Ultrasonography01:17

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Related Experiment Video

Updated: Nov 20, 2025

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
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Asymmetries in Mammography.

Brandy Johnson1

  • 1Freelance writer and editor and teaches biology courses for Central New Mexico Community College in Albuquerque. She received her PhD in Cell and Molecular Biology from Texas Tech University Health Science Center.

Radiologic Technology
|January 21, 2021
PubMed
Summary

Asymmetries on mammograms appear as denser areas in one breast. While often benign, these subtle findings can indicate breast cancer and require further diagnostic evaluation.

Area of Science:

  • Radiology
  • Medical Imaging
  • Breast Health

Background:

  • Asymmetries in mammography present as areas of increased density compared to the contralateral breast.
  • While many asymmetries are benign or summation artifacts, they can also be indicative of breast cancer.
  • The subtle nature of asymmetries makes their detection and diagnosis challenging, often mimicking normal fibroglandular tissue.

Purpose of the Study:

  • To highlight the diagnostic challenges associated with interpreting asymmetries in mammography.
  • To emphasize the importance of further evaluation for non-artifactual asymmetries detected during screening mammography.

Main Methods:

  • Review of mammographic findings related to asymmetries.
  • Discussion of differential diagnoses for asymmetries, including benign conditions and malignancy.

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  • Outline of recommended further diagnostic steps for suspicious asymmetries.

    • Main Results:

    • Asymmetries are common findings in mammography.
    • A significant proportion of asymmetries require further investigation beyond initial screening.
    • Diagnostic tools like ultrasound, MRI, and biopsy are crucial for characterizing asymmetries.

    Conclusions:

    • Asymmetries detected on screening mammography necessitate careful evaluation to differentiate benign from malignant causes.
    • Further diagnostic imaging and/or biopsy are essential for definitive diagnosis of concerning asymmetries.
    • Early and accurate detection of breast cancer through the evaluation of asymmetries is critical for patient outcomes.