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Nanosystems as curative platforms for allergic disorder management
Peng-Sheng Fan1, Meng-Jie Sun1, Di Qin1
1College of Marine Life Science, Ocean University of China, Qingdao, 266003, P. R. China. yaliu@ouc.edu.cn.
Journal of Materials Chemistry. B
|January 21, 2021
Summary
Nanoplatforms offer advanced allergy treatment by improving drug delivery and reducing side effects for conditions like allergic rhinitis and asthma. These novel approaches enhance therapeutic effectiveness and patient outcomes in managing IgE-mediated inflammatory disorders.
Area of Science:
- Immunology and Nanomedicine
- Focuses on IgE-mediated inflammatory disorders and their management.
Background:
- Allergic diseases affect billions globally, with current treatments facing limitations.
- Conventional pharmacotherapy for allergies has issues like poor drug retention and systemic side effects.
Purpose of the Study:
- To review nanoplatforms as advanced therapeutic strategies for allergy management.
- To explore nanoplatform design characteristics for various administration routes in allergy interventions.
Main Methods:
- Literature review of nanoplatform applications in allergy treatment.
- Analysis of nanoplatform characteristics for intratracheal, gastrointestinal, intravenous, and ocular delivery.
- Discussion of therapeutic strategies and recent advances.
Main Results:
- Nanoplatforms enhance solubility, in situ drug accumulation, and controlled release for allergy treatments.
- They offer multi-functional strategies to overcome limitations of conventional therapies.
- Potential for improved efficacy in allergic rhinitis, asthma, and conjunctivitis.
Conclusions:
- Nanoplatforms represent a promising therapeutic avenue for managing IgE-mediated allergic disorders.
- Further research into nanoplatform design and clinical application is warranted for effective allergy management.
- These advanced systems offer improved drug delivery and reduced side effects.
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