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Photodynamic Therapy for the Treatment of Vascularized Intraretinal Tuberculoma
Salvatore Parrulli1, Federico Zicarelli1, Alessandro Torre2
1Eye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco", Sacco Hospital, University of Milan, Milan, Italy.
Purpose:
To report a case of intraretinal tubercular granuloma successfully treated with photodynamic therapy (PDT).
Methods:
Retrospective case report. Multimodal imaging was performed at each follow-up visit.
Results:
The tuberculoma did not regress and did not significantly reduce its exudation after anti-tubercular therapy (ATT), systemic steroid therapy and intravitreal anti-VEGF. Second line treatment with PDT was attempted. The lesion showed a regression with reduced sub-retinal fluid and intra-retinal exudates. A second PDT was performed for reactivation of the lesion 5 months after the first treatment. Further regression of the lesion was observed.
Conclusion:
PDT may be a valuable second-line therapeutic approach for vascularized intraretinal granulomas.
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