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Published on: April 23, 2019
Outcomes associated with scheduling or up-scheduling controlled substances.
Jonathan P Caulkins1, Laura A Goyeneche1, Lingrong Guo1
1Carnegie Mellon University, Heinz College, 5000 Forbes Ave., Pittsburgh, PA 15213, USA.
Drug scheduling and rescheduling can significantly impact substance use, often leading to declines in the targeted drug
Area of Science:
- Pharmacology
- Public Health Policy
- Drug Control
Background:
- Nations classify drugs into schedules based on abuse risk and medical value, with varying restrictions.
- Drug rescheduling or initial scheduling aims to prevent diversion or abuse.
- Previous efforts have not synthesized lessons from diverse drug scheduling events.
Purpose of the Study:
- To analyze the effects of drug scheduling and rescheduling events.
- To identify patterns and outcomes associated with changes in drug control policies.
Main Methods:
- Conducted a systematic search for peer-reviewed evaluations of drug (re-)scheduling in the U.S. post-1969 and internationally.
- Included 109 articles from the search and 30 supplementary articles.
- Analyzed diverse outcomes and measures over different timelines.
Main Results:
- Standardization of outcomes was challenging due to diverse reporting measures.
- Over half of evaluated events showed declines in use-related measures by at least 40%.
- Substitution to other substances (sometimes more dangerous) was frequently observed, though partial.
Conclusions:
- Drug scheduling and up-scheduling can yield substantial effects on various outcomes.
- Substitution to alternative substances is a common consequence and requires anticipation in policy-making.
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