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Transvection regulates the sex-biased expression of a fly X-linked gene

Charalampos Chrysovalantis Galouzis1, Benjamin Prud'homme2

  • 1Aix-Marseille Université, CNRS, Institut de Biologie du Développement de Marseille (IBDM), Campus de Luminy Case 907, 13288 Marseille Cedex 9, France.

Science (New York, N.Y.)
|January 22, 2021
PubMed

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In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
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In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
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