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ABO blood groups and risk of covid-19

Sadok Yalaoui, Radhouane Fakhfakh, Fatma Tritar

    La Tunisie Medicale
    |January 22, 2021
    PubMed

    Insights

    This study found a higher prevalence of blood group A in Tunisian COVID-19 patients compared to controls. These findings suggest a potential link between blood group A and increased risk for coronavirus disease 2019 (COVID-19).

    Area of Science:

    • Immunology
    • Epidemiology
    • Genetics

    Background:

    • The global Coronavirus pandemic (COVID-19) has prompted extensive research.
    • Previous studies indicated a potential increased risk of COVID-19 infection in individuals with blood group A.

    Purpose of the Study:

    • To investigate the blood group phenotype distribution among Tunisian COVID-19 patients.
    • To compare the blood group profile of COVID-19 patients with control groups.

    Main Methods:

    • A cohort of 51 Tunisian patients with SARS-CoV-2 infection was analyzed.
    • Blood group distribution was compared to a control group (1506 patients) and blood donors (63375 individuals).

    Main Results:

    • A statistically significant higher prevalence of blood group A was observed in COVID-19 patients.
    • This finding was significant when compared to both Tunisian blood donors and a control group without COVID-19.

    Conclusions:

    • The study results align with existing literature, particularly larger studies from China.
    • Blood group A may be associated with an increased susceptibility to COVID-19 in the Tunisian population.
    Abstract

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