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The independent factors associated with oxygen therapy in COVID-19 patients under 65 years old

Yue-Nan Ni1, Ting Wang1, Bin-Miao Liang1

  • 1Department of Respiratory and Critical Care, West China School of Medicine and West China Hospital, Sichuan University, Chengdu, China.

Plos One
|January 22, 2021
PubMed

Insights

Hospitalized COVID-19 patients under 65 often need oxygen therapy, with fever, dyspnea, and low albumin being key risk factors. This study highlights predictors for oxygen support in younger coronavirus disease 2019 patients.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Critical Care Medicine

Background:

  • Increasing hospitalizations of young coronavirus disease 2019 (COVID-19) patients.
  • Limited specific data on hospitalized COVID-19 patients under 65 years old.

Purpose of the Study:

  • To analyze demographic, laboratory, and clinical data of COVID-19 patients under 65.
  • To identify risk factors associated with the need for oxygen therapy in this population.

Main Methods:

  • Retrospective study of 833 COVID-19 patients under 65.
  • Extraction of data from electronic medical records.
  • Statistical analysis to identify independent risk factors for oxygen therapy.

Main Results:

  • 63.1% of patients required oxygen therapy; mortality was 2.9% in this subgroup.
  • Fever, dyspnea, chest distress, elevated respiratory rate, and decreased albumin/globulin levels were significant risk factors for oxygen therapy.
  • 29.4% of patients had one or more comorbidities.

Conclusions:

  • Oxygen therapy is frequently needed for hospitalized COVID-19 patients under 65, with a high success rate.
  • Respiratory symptoms, elevated respiratory rate, low albumin/globulin, and fever predict the need for oxygen.
  • Understanding these risk factors can guide clinical management.
Abstract

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