Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biofilms01:29

Biofilms

730
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
730

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness of infection prevention and control interventions in reducing health-care-associated infections in long-term care facilities for older people: a systematic review.

The lancet. Healthy longevity·2026
Same author

Caspofungin-Based Red-Emissive Probes for Fluorescent Imaging of Pathogenic Fungi.

JACS Au·2026
Same author

Investigations into the aetiopathogenesis of orofacial granulomatosis using multiple omics technologies reveal a potential role for B cells.

Clinical and translational medicine·2026
Same author

An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen.

PLoS pathogens·2026
Same author

An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans.

Nature communications·2026
Same author

Chitosan Molecular Weight Influences on Endodontic Biofilms and Material Enhancement Strategies.

Dentistry journal·2026

Related Experiment Video

Updated: Nov 20, 2025

Clarifying and Imaging Candida albicans Biofilms
11:09

Clarifying and Imaging Candida albicans Biofilms

Published on: March 6, 2020

12.1K

Candida albicans biofilms and polymicrobial interactions.

Nicole O Ponde1, Léa Lortal1, Gordon Ramage2

  • 1Faculty of Dentistry, Oral & Craniofacial Sciences, Centre for Host-Microbiome Interactions, King's College London, London, United Kingdom.

Critical Reviews in Microbiology
|January 22, 2021
PubMed
Summary

Candida albicans can cause serious infections by forming biofilms, which are difficult to treat. This review covers biofilm formation, advantages, and interactions with other microbes.

Keywords:
Candida albicansbiofilmfungimicrobial communitypolymicrobial

More Related Videos

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
06:50

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

3.4K
Visualization of Biofilm Formation in Candida albicans Using an Automated Microfluidic Device
11:14

Visualization of Biofilm Formation in Candida albicans Using an Automated Microfluidic Device

Published on: December 14, 2017

10.9K

Related Experiment Videos

Last Updated: Nov 20, 2025

Clarifying and Imaging Candida albicans Biofilms
11:09

Clarifying and Imaging Candida albicans Biofilms

Published on: March 6, 2020

12.1K
A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
06:50

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

3.4K
Visualization of Biofilm Formation in Candida albicans Using an Automated Microfluidic Device
11:14

Visualization of Biofilm Formation in Candida albicans Using an Automated Microfluidic Device

Published on: December 14, 2017

10.9K

Area of Science:

  • Microbiology
  • Mycology
  • Infectious Diseases

Background:

  • Candida albicans is a common human commensal fungus.
  • Factors can cause C. albicans overgrowth, leading to infections from superficial to systemic.
  • Biofilm formation is a key virulence factor, posing clinical challenges due to resistance to antifungals.

Purpose of the Study:

  • To review current knowledge on Candida albicans biofilm formation and development.
  • To explore the advantages of the biofilm lifestyle for C. albicans.
  • To examine polymicrobial interactions in multispecies biofilms involving C. albicans.

Main Methods:

  • Literature review of Candida albicans biofilm research.
  • Analysis of key processes: adhesion, extracellular matrix production, and transcriptional regulation.
  • Exploration of multispecies biofilm dynamics.

Main Results:

  • Biofilm formation involves adhesion, matrix production, and complex transcriptional networks.
  • Biofilms provide survival advantages and resistance to antifungal treatments.
  • Candida albicans interacts with other microbes in multispecies biofilms, influencing infection dynamics.

Conclusions:

  • Understanding C. albicans biofilm development is crucial for combating associated infections.
  • Further research into polymicrobial interactions is needed to address clinical challenges.
  • Targeting biofilm formation presents a potential strategy for antifungal therapy.