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Updated: Nov 20, 2025

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
Published on: November 11, 2022
Facile synthesis of self-healing and layered sodium alginate/polyacrylamide hydrogel promoted by dynamic hydrogen
Dingwei Zhao1, Mi Feng1, Ling Zhang2
1Key Laboratory of Molecular Medicine and Biotherapy in the Ministry of Industry and Information Technology, School of Life Sciences, Beijing Institute of Technology, No. 5, Zhongguancun South Street, Beijing 100081, PR China.
Abstract:
Hydrogels are widely used in many fields but generally suffer from low mechanical strength and poor self-healing performance. Here, a novel and facile method was developed to prepare a semi-interpenetrating polymer network (semi-IPN) hydrogel with layered structure and improved properties based on sodium alginate (SA) and polyacrylamide (PAM). Systematic characterizations revealed a formation mechanism of layered structure via hydrogen bonds (HBs) promoted self-assembly of SA in the porous PAM matrix. Also, HBs can also display a key role in enhancing self-healing of the hydrogel, by which the hydrogel possesses a self-healing capacity of 99 % with sprayed by a few of water. Moreover, the layered semi-IPN structure makes the tensile strength of PAMSA hydrogel reach 266 kPa. The fabricated PAMSA hydrogel with layered microstructure containing SA provides a protocol to broaden the functionality and variety of the hydrogels.
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