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Personalising sarcoma care using quantitative multimodality imaging for response assessment.

G M Kalisvaart¹, J L Bloem¹, J V M G Bovée²

¹Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.

Clinical Radiology

|January 23, 2021

Summary

This summary is machine-generated.

Advanced medical imaging techniques aid in personalizing cancer medicine for sarcoma patients. This review explores how imaging can guide treatment adaptation by assessing tumor response, improving patient care.

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Area of Science:

Radiology and Oncology
Medical Imaging in Personalized Medicine

Background:

Technological advancements in radiology have increased the use of imaging for personalized oncology, particularly for sarcoma patients.
Imaging enables the assessment of tumor physical and biological properties, crucial for evaluating treatment response.

Purpose of the Study:

To review current clinical data on imaging-based response monitoring in sarcoma patients.
To identify challenges and future research directions for utilizing imaging in sarcoma treatment adaptation.

Main Methods:

Comprehensive literature review of clinical data on imaging-based response monitoring in sarcoma.
Analysis of technological developments including hardware, protocols, algorithms, radiotracers, and contrast media.

Main Results:

Medical imaging holds significant potential for selecting sarcoma patients who may not benefit from neoadjuvant or adjuvant treatments.
Developing a practical set of imaging features for specific sarcoma subtypes is essential for accurate response assessment due to tumor heterogeneity.

Conclusions:

Imaging-based response monitoring is expected to facilitate successful modification of neoadjuvant treatments.
The integration of advanced imaging techniques promises to improve clinical care and outcomes for sarcoma patients.