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Myocarditis in COVID-19 patients: current problems

Donato Mele1, Filippo Flamigni2, Claudio Rapezzi2,3

  • 1Cardiology Center, University of Ferrara, Viale Aldo Moro 8, 44024, Cona, Ferrara, Italy. donatomele@libero.it.

Internal and Emergency Medicine
|January 23, 2021
PubMed

Insights

Myocarditis, inflammation of the heart muscle, can occur in patients with COVID-19. This review summarizes current knowledge on its diagnosis and treatment in these patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Virology

Background:

  • Myocarditis is a potential complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
  • Limited information exists regarding the mechanisms, prevalence, prognosis, diagnosis, and therapy of COVID-19-associated myocarditis.
  • Physicians require updated knowledge to manage this condition effectively.

Purpose of the Study:

  • To review and synthesize current scientific knowledge on myocarditis in patients with COVID-19.
  • To highlight challenges and gaps in the diagnosis and treatment of this condition.

Main Methods:

  • Literature review of existing studies on myocarditis and COVID-19.
  • Synthesis of data on clinical presentation, diagnosis, and management strategies.

Main Results:

  • COVID-19 can present as or lead to myocarditis.
  • Significant gaps in understanding the underlying mechanisms and epidemiological data persist.
  • Diagnostic criteria and therapeutic approaches require further clarification and standardization.

Conclusions:

  • Myocarditis is a recognized clinical entity in COVID-19 patients.
  • Further research is crucial to elucidate mechanisms, establish prevalence, and optimize diagnostic and therapeutic protocols.
  • Addressing these knowledge gaps is essential for improving patient outcomes.

Keywords:
COVID-19EndotheliitisMyocarditisSARS-CoV-2

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