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Targeting of uncontrolled hypertension in the emergency department (TOUCHED): Design of a randomized controlled trial

Heather M Prendergast1, Renee Petzel-Gimbar2, Spyros Kitsiou3

  • 1Department of Emergency Medicine, University of Illinois, Chicago, IL, USA.

Contemporary Clinical Trials
|January 23, 2021
PubMed

Insights

The TOUCHED trial tested an Educational and Empowerment intervention for uncontrolled hypertension in the Emergency Department (ED). This intervention aims to improve blood pressure control in high-risk populations, potentially reducing cardiovascular risks.

Area of Science:

  • Cardiology
  • Public Health
  • Health Disparities

Background:

  • Uncontrolled or undiagnosed hypertension (HTN) affects up to 46% of emergency department (ED) patients.
  • HTN significantly increases cardiovascular morbidity and disproportionately impacts minority communities.
  • EDs are crucial for identifying and treating high-risk populations with uncontrolled HTN.

Purpose of the Study:

  • To evaluate the effectiveness of the Targeting of UnControlled Hypertension in the Emergency Department (TOUCHED) trial.
  • To assess a novel Educational and Empowerment (E2) intervention for uncontrolled HTN.
  • To reduce disparities in HTN control among high-risk ED populations.

Main Methods:

  • A randomized controlled trial involving 770 adults aged 18-75 with uncontrolled HTN.
  • Comparison of usual care versus an E2 intervention including a Post-Acute Care Hypertension Consultation (PACHT-c) and mobile health BP monitoring.
  • Primary outcome: difference in mean systolic blood pressure (SBP) at 6 months.

Main Results:

  • The study is designed to determine the effectiveness of the intervention.
  • Secondary outcomes include changes in SBP and diastolic blood pressure (DBP) at 3 and 6 months.
  • Improvements in cardiovascular risk, medication adherence, primary care engagement, and HTN knowledge will be assessed.

Conclusions:

  • The TOUCHED trial will establish the efficacy of a brief, ED-based intervention for uncontrolled HTN.
  • Findings will inform the scalability of this intervention to other urban EDs.
  • This study aims to provide a critical intervention for high-risk populations often underserved by traditional healthcare settings.
Abstract

Keywords:
Clinical trialHypertensionStudy designSubject recruitment

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