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Updated: Aug 28, 2026

The Intra-Aortic Balloon Pump
Published on: February 5, 2021
Infected aortobifemoral prosthesis--a dreaded complication
J Schellack1, M T Stewart, R B Smith
1Department of Surgery, Emory University School of Medicine, Atlanta, Georgia.
Abstract:
From 1980 to 1985 13 patients were identified with infected aortofemoral grafts. Potential predisposing factors identified included a history of multiple femoral arterial procedures (10 patients; 77%) as well as perioperative infections occurring at the time of a prior femoral operation (five patients; 38%). Patients presented with suppurative groin infections (11) or ruptured pseudoaneurysms (2). Two who had previously undergone bilateral amputations were managed by removal of their aortic grafts without revascularization. Eleven other patients were managed by excision of the entire prosthesis (6 aortic grafts), partial graft excision (five graft limbs) or local treatment alone (three graft limbs). Revascularization through uninfected tissue planes was performed on 14 limbs with salvage of 11 (limb salvage 79%); whereas three limbs not revascularized required major amputation (limb salvage 0%). Despite an aggressive surgical approach five patients (38%) required a major amputation and there were three deaths (23% mortality). Once the diagnosis of an infected graft is made, early graft excision and prompt revascularization are encouraged.
Insights
Infected aortofemoral grafts require prompt surgical intervention. Early graft excision and revascularization significantly improve limb salvage rates, though amputation and mortality remain risks.
Area of Science:
- Vascular Surgery
- Infectious Disease Management
Background:
- Infected aortofemoral grafts pose a significant challenge in vascular surgery.
- Predisposing factors include prior femoral procedures and perioperative infections.
Purpose of the Study:
- To evaluate the outcomes of managing infected aortofemoral grafts.
- To identify factors influencing limb salvage and mortality.
Main Methods:
- Retrospective review of 13 patients with infected aortofemoral grafts (1980-1985).
- Analysis of management strategies including graft excision and revascularization.
- Assessment of predisposing factors, presentation, and outcomes.
Main Results:
- Suppurative groin infections (11) and ruptured pseudoaneurysms (2) were common presentations.
- Graft excision with revascularization achieved 79% limb salvage.
- Major amputation was required in 38% of patients, with a 23% mortality rate.
Conclusions:
- Early graft excision and prompt revascularization are crucial for managing infected aortofemoral grafts.
- Aggressive surgical management is necessary despite associated risks of amputation and mortality.
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