Related Experiment Video
Updated: Aug 10, 2026

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
Published on: October 22, 2015
Long term follow up of patients with early onset anorexia nervosa
R Bryant-Waugh1, J Knibbs, A Fosson
1Department of Psychological Medicine, Hospital for Sick Children, London.
Insights
A long-term study of 30 children with anorexia nervosa found that only 60% had a good outcome. Early onset and family issues were linked to poor prognosis in pediatric anorexia nervosa.
Area of Science:
- Child and Adolescent Psychiatry
- Eating Disorders Research
- Longitudinal Studies in Pediatrics
Background:
- Anorexia nervosa is a serious eating disorder affecting children and adolescents.
- Long-term outcomes for pediatric anorexia nervosa require further investigation.
- Understanding prognostic factors is crucial for early intervention.
Purpose of the Study:
- To assess the long-term outcomes of children diagnosed with anorexia nervosa.
- To identify factors associated with poor prognosis in pediatric anorexia nervosa.
Main Methods:
- A cohort of 30 children with anorexia nervosa underwent long-term follow-up (mean 7.2 years).
- Data collected included age at onset, presence of depression, family environment, and parental marital history.
- Statistical analysis was performed to identify prognostic indicators.
Main Results:
- Good outcomes were observed in 60% (18 children) of the cohort.
- Ten children remained moderately to severely impaired.
- Two children died during the follow-up period.
- Poor prognostic factors identified include early age at onset (<11 years), comorbid depression, disturbed family life, single-parent households, and parental remarriage.
Conclusions:
- Pediatric anorexia nervosa has a significant long-term morbidity and mortality.
- Early age at onset and adverse family circumstances are critical indicators of poor prognosis.
- Targeted interventions addressing these factors may improve long-term outcomes for children with anorexia nervosa.
Abstract:
A long term follow up (mean 7.2 years) of 30 children with anorexia nervosa (mean age at onset 11.7 years) was carried out. The outcome was good in only 18 (60%), 10 children remaining moderately to severely impaired and two died. Poor prognostic factors included early age at onset (less than 11 years), depression during the illness, disturbed family life and one parent families, and those in which one or both parents had been married before.
Related Concept Videos
Longitudinal Research
Binge Eating Disorders

