Related Experiment Video
Updated: Nov 20, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Hemecitones A and B: two phenanthrenes with cytotoxicity from Hemerocallis fulva (L.) L
Rao Fu1, Xia Wang1, Biao Zhao1
1Department of Traditional Chinese Medicine, Sichuan Cancer Hospital, Chengdu, P.R. China.
Abstract:
Two new phenanthrenes, Hemecitones A and B, were isolated from Hemerocallis fulva (L.) L. Their structures were determined by UV, IR, HR-ESI-MS, 1D and 2D NMR analysis. The in vitro cytotoxic activities of compounds 1 and 2 were studied against breast carcinoma MDA-MB-231, hepatocellular carcinoma HepG2 and lung carcinoma A549 cell lines. And compounds 1 and 2 exhibited anti-proliferative effects against these least one of the three types of cell lines with IC50 ranging from 12.57 ± 2.34 to 31.22 ± 1.36 μM.[Formula: see text].
Related Concept Videos
Physical Properties of Amines
Aromatic Hydrocarbon Cations: Structural Overview
Removing one hydrogen from the intervening CH2 group...
Criteria for Aromaticity and the Hückel 4n + 2 Rule
For the first time, Eric Hückel, a German chemical physicist, derived a set of structural features for a compound to be classified as aromatic. This is now known as Hückel’s rule or the 4n +...
Thermal and Photochemical Electrocyclic Reactions: Overview
Benzene to Phenol via Cumene: Hock Process
Five-Membered Heterocyclic Aromatic Compounds: Overview

![Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60786.jpg&w=3840&q=50)