Related Experiment Video
Updated: Nov 20, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Vitamin D, the natural way
1Centro de Salud Puerta de Madrid, Atención Primaria de, Madrid, Spain.
Background & Aims:
Vitamin D is a fat-soluble vitamin whose main function in the body is the regulation of bone mineral metabolism. In the last two decades, there has been an intensive research for possible vitamin D benefits in non-skeletal health but as today it still remains unclear. The aim of this article is to review vitamin D metabolism and the natural sources to encourage lifestyle changes to avoid deficiency.
Review:
Universal screening for vitamin D deficiency is not warranted and it should only be done in cases with risk factors for vitamin deficiency. Vitamin D is measured in the body by determining 25-hydroxycholecalciferol; values below 20 ng/mL (50 nmol/L) are considered inadequate. The three sources of vitamin D are the ultraviolet sun radiation, diet and supplementation. The role of vitamin D supplementation out of the osteoporosis treatment and prevention still remain controversial. Healthy sun exposure and diet should be discussed with all patients with vitamin D deficiency and in general population in promoting health. The skin, through solar radiation, is the main source of vitamin D and provides 90% of the body's needs.
Conclusions:
Changing lifestyle habits, encouraging a controlled sun exposure and proper vitamin D diet is a preventive strategy that should be applied in our daily practice to prevent osteoporosis and other diseases associated with low vitamin D.
More Related Videos
06:47Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
05:03Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling
Published on: December 27, 2024
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Vitamins
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Amino Acid Biosynthetic Pathways
Proteins: Dietary Sources and Requirements
Lipids: Dietary Sources and Requirements