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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Vitamins01:30

Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
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Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Amino Acid Biosynthetic Pathways01:29

Amino Acid Biosynthetic Pathways

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Amino acid biosynthesis is essential for cell growth, protein synthesis, and metabolic regulation. Cells generate essential and non-essential amino acids from metabolic intermediates to sustain vital biological functions. These intermediates originate from key metabolic pathways: glycolysis, the tricarboxylic acid (TCA) cycle, and the pentose phosphate pathway. Important precursors include α-ketoglutarate, pyruvate, oxaloacetate, phosphoenolpyruvate, and erythrose-4-phosphate, which...
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Proteins: Dietary Sources and Requirements01:28

Proteins: Dietary Sources and Requirements

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Consuming animal-based products offers high-quality proteins that contain optimal levels and combinations of essential amino acids, crucial for tissue repair and growth. Foods like eggs, milk, fish, and most meats are a source of complete proteins. Legumes and cereals are abundant in proteins; however, they typically lack a full range of essential amino acids. As a result, they are considered incomplete protein sources. Some plant sources like soybeans, quinoa, and amaranth do contain complete...
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Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

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Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ...
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Updated: Nov 20, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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Vitamin D, the natural way.

Antonio L Aguilar-Shea1

  • 1Centro de Salud Puerta de Madrid, Atención Primaria de, Madrid, Spain.

Clinical Nutrition ESPEN
|January 25, 2021
PubMed
Summary

Promoting healthy lifestyle habits, including adequate sun exposure and a vitamin D-rich diet, is crucial for preventing deficiency and maintaining bone health. These lifestyle changes are recommended to avoid potential health issues linked to low vitamin D levels.

Area of Science:

  • Endocrinology
  • Nutritional Science
  • Public Health

Background:

  • Vitamin D is essential for bone mineral metabolism.
  • Research into non-skeletal benefits of vitamin D is ongoing but inconclusive.
  • Vitamin D deficiency remains a public health concern.

Purpose of the Study:

  • To review vitamin D metabolism and natural sources.
  • To encourage lifestyle modifications for preventing vitamin D deficiency.
  • To discuss the role of vitamin D in skeletal and non-skeletal health.

Main Methods:

  • Literature review on vitamin D metabolism and sources.
  • Analysis of current guidelines for vitamin D screening.
  • Discussion of dietary and lifestyle recommendations.
Keywords:
SunlightUltraviolet raysVitamin DVitamin D deficiency

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Main Results:

  • Vitamin D deficiency screening is recommended only for individuals with risk factors.
  • 25-hydroxycholecalciferol levels below 20 ng/mL indicate inadequacy.
  • Sun exposure and diet are primary natural sources of vitamin D.

Conclusions:

  • Lifestyle changes, including controlled sun exposure and diet, are key preventive strategies.
  • Promoting adequate vitamin D intake can help prevent osteoporosis and other related diseases.
  • Public health initiatives should focus on educating individuals about vitamin D sufficiency.