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Related Concept Videos

Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

129
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
129
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

133
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
133
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

141
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
141
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

124
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
124
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

107
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
107
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

553
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
553

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Tuberous Sclerosis Complex (TSC): Renal and Extrarenal Imaging.

Shiva Gupta1, Hyunseon C Kang2, Silvana C Faria2

  • 1Department of Abdominal Imaging, Unit 1473, University of Texas MD Anderson Cancer Center; 1515 Holcombe Blvd, Houston, TX..

Academic Radiology
|January 25, 2021
PubMed
Summary

Tuberous sclerosis complex (TSC) can cause kidney tumors, a major cause of death. Early diagnosis and understanding of renal masses are crucial for managing this rare but serious complication.

Keywords:
kidneyrenal cell carcinomatargeted therapytuberous sclerosis complex

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Area of Science:

  • Oncology
  • Nephrology
  • Genetics

Background:

  • Tuberous sclerosis complex (TSC) is a genetic disorder causing tumors in multiple organs.
  • Renal complications are a primary cause of mortality in TSC patients.
  • Renal cell carcinoma (RCC) occurs in 2-4% of TSC patients, significantly impacting morbidity and mortality.

Purpose of the Study:

  • To review the pathogenesis and management of renal abnormalities in TSC.
  • To highlight the diagnostic importance of extrarenal manifestations.
  • To emphasize the significance of renal mass types in TSC management.

Main Methods:

  • Literature review on TSC, renal manifestations, and RCC.
  • Analysis of diagnostic criteria and management strategies.
  • Discussion of tumor pathogenesis and classification.

Main Results:

  • Renal abnormalities are a leading cause of death in TSC.
  • RCC, though uncommon, is a significant contributor to TSC-related mortality.
  • Extrarenal TSC manifestations aid in diagnosis.

Conclusions:

  • Effective management of TSC-related renal masses is critical for improving patient outcomes.
  • Understanding the specific types of renal masses is essential for tailored treatment.
  • Integrated diagnostic and management approaches are necessary for TSC patients with renal involvement.