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Cardiovascular Complications of COVID-19 and Associated Concerns: A Review

Wen-Liang Yu1,2, Han Siong Toh1,3, Chia-Te Liao4,5

  • 1Department of Intensive Care Medicine, Chi Mei Medical Center, Tainan.

Acta Cardiologica Sinica
|January 25, 2021
PubMed

Insights

This review details coronavirus disease 2019 (COVID-19) impacts on the cardiovascular system. It covers COVID-19 epidemiology, complications, mechanisms, and treatments, emphasizing heart damage from the virus and cytokine storm.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Virology

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has profoundly impacted global health.
  • SARS-CoV-2 significantly affects the cardiovascular system, leading to severe complications.
  • Both direct viral injury and the ensuing cytokine storm contribute to cardiac damage.

Purpose of the Study:

  • To provide a comprehensive review of current knowledge on COVID-19.
  • To focus specifically on the cardiovascular implications of SARS-CoV-2 infection.
  • To summarize recent therapeutic strategies for COVID-19.

Main Methods:

  • Literature review of pivotal findings on COVID-19.
  • Synthesis of epidemiological data.
  • Analysis of mechanisms and complications, particularly cardiovascular effects.
  • Review of recent therapeutic interventions.

Main Results:

  • COVID-19 presents diverse cardiovascular complications.
  • Mechanisms include direct viral invasion and inflammatory responses (cytokine storm).
  • Emerging therapies aim to mitigate viral spread and inflammatory damage.

Conclusions:

  • Understanding COVID-19's cardiovascular impact is crucial for patient management.
  • Effective anti-SARS-CoV-2 treatments are essential for controlling the pandemic.
  • Further research is needed to fully elucidate and manage COVID-19-related cardiac issues.

Keywords:
COVID-19Cardiovascular injuriesCytokine stormTherapies

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