Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Eukaryotic Promoter Region02:40

The Eukaryotic Promoter Region

18.1K
The eukaryotic promoter region is a segment of DNA located upstream of a gene. It contains an RNA polymerase binding site, a transcription start site, and several cis-regulatory sequences.  The proximal promoter region is located in the vicinity of the gene and has cis-regulatory sequences and the core promoter. The core promoter is the binding site for RNA polymerase and is usually located between -35 and +35 nucleotides from the transcription start site. The distal promoter regions are...
18.1K
The Eukaryotic Promoter Region02:40

The Eukaryotic Promoter Region

3.6K
3.6K
Cell Signaling in Plants01:25

Cell Signaling in Plants

6.0K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
6.0K
Neural Circuits01:25

Neural Circuits

2.2K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
2.2K
Transcription Initiation01:47

Transcription Initiation

18.4K
Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
The promoters and enhancers and their accessory proteins allow tight regulation of...
18.4K
Classification of Neurotransmitters01:30

Classification of Neurotransmitters

4.5K
Neurotransmitters play a crucial role in the communication between neurons in the autonomic nervous system. Neurons in the autonomic nervous system can be cholinergic or adrenergic depending on the neurotransmitters synthesized. Cholinergic neurons use acetylcholine as their primary neurotransmitter. This includes all the preganglionic fibers of the sympathetic and pre- and postganglionic fibers of the parasympathetic nervous systems. In addition, neurons of the somatic nervous system also use...
4.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Screening of glucose-6-phosphate dehydrogenase deficiency in a cohort of 215,137 newborns: an epidemiological and pathogenic variant spectrum study in Yueyang, China.

Frontiers in genetics·2026
Same author

The Impact of Institutional Volume on Transcatheter Aortic Valve Replacement Outcomes.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2026
Same author

Effect of electronic cigarette aerosols on cisplatin resistance in head and neck cancer cells: a collaborative replication study.

BMC cancer·2026
Same author

Impact of Electronic Cigarette Use on the Oral Microbiota: A Systematic Review.

Journal of clinical periodontology·2026
Same author

Systematic evaluation of computational methods for cell segmentation.

Briefings in bioinformatics·2026
Same author

Functional characterization of antennae-enriched chemosensory protein 4 in emerald ash borer, <i>Agrilus planipennis</i>.

PeerJ·2025

Related Experiment Video

Updated: Nov 20, 2025

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
10:16

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions

Published on: June 28, 2018

33.0K

iPTT(2 L)-CNN: A Two-Layer Predictor for Identifying Promoters and Their Types in Plant Genomes by Convolutional

Ang Sun1, Xuan Xiao1, Zhaochun Xu1

  • 1Jing-De-Zhen Ceramic Institute, Jingdezhen, China.

Computational and Mathematical Methods in Medicine
|January 25, 2021
PubMed
Summary

This study introduces iPTT(2L)-CNN, a new computational tool for identifying gene promoters and distinguishing between TATA and TATA-less types. This advancement aids in understanding transcriptional regulation and developing new biological insights.

More Related Videos

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants
06:34

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants

Published on: January 21, 2020

8.6K
Plant Promoter Analysis: Identification and Characterization of Root Nodule Specific Promoter in the Common Bean
10:58

Plant Promoter Analysis: Identification and Characterization of Root Nodule Specific Promoter in the Common Bean

Published on: December 23, 2017

12.9K

Related Experiment Videos

Last Updated: Nov 20, 2025

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
10:16

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions

Published on: June 28, 2018

33.0K
A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants
06:34

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants

Published on: January 21, 2020

8.6K
Plant Promoter Analysis: Identification and Characterization of Root Nodule Specific Promoter in the Common Bean
10:58

Plant Promoter Analysis: Identification and Characterization of Root Nodule Specific Promoter in the Common Bean

Published on: December 23, 2017

12.9K

Area of Science:

  • Genomics
  • Bioinformatics
  • Molecular Biology

Background:

  • Promoters are crucial DNA sequences initiating gene transcription.
  • Accurate promoter identification is vital for understanding gene regulation.
  • Existing tools often lack the ability to differentiate promoter types like TATA and TATA-less.

Purpose of the Study:

  • To develop an accurate in silico tool for identifying both promoters and their types (TATA vs. TATA-less).
  • To address the limitations of current prediction methods in classifying promoter subtypes.

Main Methods:

  • Development of a two-layer predictor, iPTT(2L)-CNN, utilizing convolutional neural networks (CNN).
  • The first CNN layer distinguishes promoters from non-promoters.
  • The second CNN layer classifies identified promoters as TATA or TATA-less.

Main Results:

  • The iPTT(2L)-CNN predictor demonstrated promising performance in identifying promoters.
  • The tool accurately classified promoters into TATA and TATA-less types.
  • Validation through 5-fold cross-validation and independent testing confirmed its efficacy.

Conclusions:

  • The iPTT(2L)-CNN is an effective computational tool for promoter identification and classification.
  • This tool can significantly aid researchers in studying transcriptional regulation.
  • A user-friendly web server is available for experimental scientists.