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Updated: Nov 20, 2025

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
An unusual and severe case of paclitaxel-induced hand-foot syndrome
Ichrak Ben Abdallah1, Sonia Ben Nasr1, Aref Zribi1
1Department of medical oncology Faculty of medicine of Tunis Military Hospital of Tunis University Tunis El-Manar Tunis Tunisia.
Abstract:
Although paclitaxel is known to cause mild skin toxicity, it may induce severe HFS requiring drug withdrawal. Patients with high disease burden might receive prolonged paclitaxel chemotherapy. Hence, a grade 2 toxicity would better indicate withdrawal of paclitaxel instead of suspension and rechallenge, to prevent such severe HFS requiring long-time recovery.
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