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Pancytopenia revealing acute brucellosis
Yassine Ben Lahlou1,2, Elmostafa Benaissa1,2, Adil Maleb3
1Epidemiology and Bacterial Resistance Research Team/BIO-INOVA Centre, Faculty of Medicine and Pharmacy (University Mohammed V), Rabat, Morocco.
Idcases
|January 25, 2021
Summary
Brucellosis, a common bacterial zoonosis, can cause pancytopenia. Prompt diagnosis and antibiotic treatment led to a full recovery in a 73-year-old male patient.
Area of Science:
- Infectious Diseases
- Hematology
- Zoonotic Diseases
Background:
- Brucellosis is a significant global bacterial zoonosis, with over 500,000 estimated annual cases worldwide.
- Hematological abnormalities, including anemia and leukopenia, are common in acute brucellosis.
- Pancytopenia and thrombocytopenia are less frequently observed complications of brucellosis.
Observation:
- A case report of a 73-year-old male patient presenting with pancytopenia is described.
- The patient's pancytopenia was revealed to be caused by acute brucellosis.
Findings:
- The patient received 6 weeks of antibiotic therapy for acute brucellosis.
- Following treatment, the patient experienced a favorable clinical outcome.
- Complete blood count normalized after the antibiotic course.
Implications:
- Acute brucellosis should be considered in the differential diagnosis of patients presenting with pancytopenia.
- Early suspicion and treatment of brucellosis can lead to positive patient outcomes.
- This case highlights the importance of recognizing less common hematological manifestations of brucellosis.

