Related Experiment Video
Updated: Nov 20, 2025

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
Published on: May 10, 2024
Empagliflozin-Associated Pancreatitis: A Consideration for SGLT2 Inhibitors
Karolina N Dziadkowiec1, Peter M Stawinski1, Jose Proenza2
1The University of Miami, JFK Regional Campus, Division of Internal Medicine, Lake Worth, FL.
Abstract:
Empagliflozin belongs to a class of sodium-glucose cotransporter-2 inhibitors, a medication approved by the US Food and Drug Administration in 2014 for the treatment of type 2 diabetes mellitus. Well-known side effects of this medication include symptomatic hypotension, hypoglycemia, and urinary tract infections among others. We present a case of severe epigastric abdominal pain consistent with acute pancreatitis in the setting of empagliflozin use, suggesting a possible drug-induced acute pancreatitis.
Related Concept Videos
Dipeptidyl Peptidase 4 Inhibitors
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...
Oral Hypoglycemic Agents: Biguanides and Glitazones
Oral Hypoglycemic Agents: Glinides
Acute Pancreatitis II: Clinical Manifestations and Management
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
Acarbose and miglitol are...

