Data regarding 2D:4D and other digit ratios in Greek population

Area of Science:

• Anthropometry
• Endocrinology
• Human Biology

Background:

• The second-to-fourth digit ratio (2D:4D) is a recognized sexually dimorphic biometric marker.
• It is influenced by prenatal hormone levels, particularly estrogen, reflecting an individual's hormonal profile.
• Past exposure to environmental estrogens, known endocrine disruptors, may have long-term feminizing effects and health implications.

Purpose of the Study:

• To investigate the influence of age on the 2D:4D ratio in a Greek population.
• To explore potential correlations between age-related hormonal changes and digit ratios.
• To assess the impact of historical environmental estrogen exposure on biometric markers.

Main Methods:

• A stratified random sample of 160 Greek individuals was recruited.
• Finger lengths were precisely measured using an electronic caliper.
• Statistical analysis was performed, dividing the sample into three age subgroups: ≤37, 38-63, and ≥64 years.

Main Results:

• A significantly higher 2D:4D ratio was observed in the middle-aged group (38-63 years) compared to other age groups.
• Sexual dimorphism in the 2D:4D ratio remained consistent across all age groups.
• Other digit ratios followed a similar pattern, with younger (<38 years) and older (≥64 years) individuals exhibiting comparable ratios.

Conclusions:

• Age significantly influences the 2D:4D ratio in the Greek population, with middle-aged individuals exhibiting distinct ratios.
• The findings suggest that early-life hormonal environment, potentially including historical exposure to endocrine disruptors, may have lasting effects on adult anthropometric markers.
• Further research is warranted to elucidate the specific mechanisms and long-term health consequences associated with these age-related variations in digit ratios.