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Updated: Nov 20, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Pancreatic cancer masquerading as ischemic enteritis on endoscopy
Enrik John T Aguila1, Carlos Paolo D Francisco1, Jonard T Co1
1Institute of Digestive and Liver Diseases St. Luke's Medical Center Global City Taguig Philippines.
Pancreatic cancer rarely presents as ischemic enteritis due to artery invasion. This case highlights pancreatic adenocarcinoma initially mimicking ischemic enteritis, diagnosed via enteroscopy and endoscopic ultrasound.
Area of Science:
- Gastroenterology
- Oncology
- Diagnostic Imaging
Background:
- Pancreatic tumors typically cause painless jaundice and may lead to bowel obstruction.
- Ischemic enteritis from pancreatic malignancy invading major arteries is exceptionally rare.
- Endoscopic documentation of this presentation has not been previously reported.
Observation:
- A computed tomography (CT) scan revealed duodenal and jejunal wall thickening.
- Enteroscopy showed a poorly distensible duodenum with purplish mucosa.
- Mesenteric CT angiography demonstrated pancreatic head mass encasing the superior mesenteric artery.
Findings:
- Pancreatic adenocarcinoma was diagnosed via endoscopic ultrasound (EUS)-guided fine-needle biopsy.
- The tumor presented atypically, mimicking ischemic enteritis.
- EUS identified a hypoechoic lesion in the pancreatic head.
Implications:
- This case expands the known clinical presentations of pancreatic adenocarcinoma.
- It underscores the importance of advanced endoscopic techniques in diagnosing rare gastrointestinal pathologies.
- Early and accurate diagnosis is crucial for effective pancreatic cancer management.
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