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Updated: Nov 20, 2025

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Regression of severe heart failure after combined left ventricular assist device placement and sleeve gastrectomy
Sriram S Nathan1, Pouya Iranmanesh2, Igor D Gregoric1
1Department of Advanced Cardiopulmonary Therapies and Transplantation, UTHealth, 6400 Fannin St, Suite 2350, Houston, TX, 77030, USA.
Abstract:
Patients who suffer morbid obesity and heart failure (HF) present unique challenges. Two cases are described where concomitant use of laparoscopic sleeve gastrectomy (LSG) and left ventricular assist device (LVAD) placement enabled myocardial recovery and weight loss resulting in explantation. A 29-year-old male patient with a body mass index (BMI) of 59 kg/m2 and severe HF with a left ventricular ejection fraction (LVEF) of 20-25% underwent concomitant LSG and LVAD placement. Sixteen months after surgery, his BMI was reduced to 34 kg/m2 and his LVEF improved to 50-55%. A second 41-year-old male patient with a BMI of 44.8 kg/m2 with severe HF underwent the same procedures. Twenty-four months later, his BMI was 31.1 kg/m2 and his LVEF was 50-55%. In both cases, the LVAD was successfully explanted and patients remain asymptomatic. HF teams should consult and collaborate with bariatric experts to determine if LSG may improve the outcomes of their HF patients.
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