Staphylococcus aureus meningitis complicated with intracranial hemorrhage and cerebral infarction: a case report

Yu Jia1, Wei Wang2, Xiangbo Wang1

  • 1Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Abstract

Insights

Staphylococcus aureus meningitis with cerebrovascular complications like hemorrhage and infarction is rare. Prompt diagnosis and treatment of this severe infection are crucial for patient recovery and improved outcomes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Neurology

Background:

  • Staphylococcus aureus meningitis is a serious infection.
  • Cerebrovascular complications in meningitis are associated with poor prognosis.
  • Meningitis with intracranial hemorrhage and cerebral infarction is exceptionally rare.

Observation:

  • A young male presented with prolonged fever, altered consciousness, and focal neurological deficits.
  • Brain imaging revealed intracranial hemorrhage and multiple cerebral infarctions.
  • Cerebrospinal fluid analysis showed elevated white blood cells and protein, with low glucose.

Findings:

  • Cultures of cerebrospinal fluid and a foot blister confirmed Staphylococcus aureus infection.
  • The patient exhibited signs of cognitive dysfunction, hemiplegia, and meningeal irritation.
  • Treatment with meropenem and glucocorticoids led to clinical improvement.

Implications:

  • Early identification of the causative pathogen is critical for effective treatment.
  • Timely diagnosis and management of Staphylococcus aureus meningitis with cerebrovascular complications can improve patient outcomes.
  • This case highlights the importance of considering serious neurological complications in patients with bacterial meningitis.

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