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Staphylococcus aureus meningitis complicated with intracranial hemorrhage and cerebral infarction: a case report
Yu Jia1, Wei Wang2, Xiangbo Wang1
1Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Purpose:
The case with staphylococcus aureus meningitis accompanied by intracranial hemorrhage and cerebral infarction is very rare and cerebrovascular complications are often associated with poor outcome.
Materials And Methods:
We describe the clinical characteristics and laboratory data of a patient with meningitis accompanied by cerebrovascular complications.
Results:
The patient, a young male, was admitted to hospital with 3 weeks of fever, 10 days of slow reaction and 2 days of left limb strength decline. Neurological examination showed cognitive dysfunction, left central hemiplegia and meningeal irritation sign. Brain Imaging examination revealed intracranial hemorrhage and multiple cerebral infarction. The elevated leucocyte and protein, as well as low glucose of cerebrospinal fluid was observed. Cerebrospinal fluid and foot blister culture both suggested staphylococcus aureus infection. With the treatment of meropenem and glucocorticoid, the condition of our patient was improved.
Conclusions:
Detection of pathogenic bacteria is the gold standard of diagnosis, and timely diagnosis and treatment for pathogens are the keys to a good prognosis for patients.
Insights
Staphylococcus aureus meningitis with cerebrovascular complications like hemorrhage and infarction is rare. Prompt diagnosis and treatment of this severe infection are crucial for patient recovery and improved outcomes.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Neurology
Background:
- Staphylococcus aureus meningitis is a serious infection.
- Cerebrovascular complications in meningitis are associated with poor prognosis.
- Meningitis with intracranial hemorrhage and cerebral infarction is exceptionally rare.
Observation:
- A young male presented with prolonged fever, altered consciousness, and focal neurological deficits.
- Brain imaging revealed intracranial hemorrhage and multiple cerebral infarctions.
- Cerebrospinal fluid analysis showed elevated white blood cells and protein, with low glucose.
Findings:
- Cultures of cerebrospinal fluid and a foot blister confirmed Staphylococcus aureus infection.
- The patient exhibited signs of cognitive dysfunction, hemiplegia, and meningeal irritation.
- Treatment with meropenem and glucocorticoids led to clinical improvement.
Implications:
- Early identification of the causative pathogen is critical for effective treatment.
- Timely diagnosis and management of Staphylococcus aureus meningitis with cerebrovascular complications can improve patient outcomes.
- This case highlights the importance of considering serious neurological complications in patients with bacterial meningitis.
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