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Reimbursement Matters: Overcoming Barriers to Clinical Trial Accrual

Simon J Craddock Lee1,2, Caitlin C Murphy1,2, David E Gerber1,2,3

  • 1Department of Population & Data Sciences, University of Texas Southwestern Medical Center.

Medical Care
|January 25, 2021
PubMed
Abstract

Insights

Financial reimbursement could improve cancer clinical trial accrual by enhancing infrastructure. However, oncologists express significant concerns regarding potential conflicts of interest, necessitating careful consideration in any new reimbursement system.

Area of Science:

  • Oncology
  • Clinical Trials
  • Healthcare Economics

Background:

  • Cancer clinical trial accrual rates are suboptimal.
  • Limited data exist on the impact of financial reimbursement on trial accrual.

Purpose of the Study:

  • To assess oncologists' perceptions of reimbursement as a strategy to overcome barriers to clinical trial accrual.
  • To identify specific barriers to trial enrollment and how reimbursement might address them.

Main Methods:

  • A cross-sectional survey was conducted among oncologists identified from the American Medical Association Physician Masterfile.
  • Descriptive statistics and analyses of physician characteristics associated with perceptions of reimbursement were performed.

Main Results:

  • Most respondents were medical oncologists; 30% discussed trials with over 25% of patients.
  • Perceived barriers included administrative/regulatory issues, physician/staff time, and eligibility criteria.
  • While oncologists believe reimbursement could improve infrastructure, significant ethical concerns about conflicts of interest were noted for both discussion and accrual reimbursement.

Conclusions:

  • Oncologists support reimbursement for enhancing clinical trial infrastructure to overcome accrual barriers.
  • Addressing ethical concerns, particularly potential conflicts of interest, is paramount for implementing any reimbursement system.

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