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Updated: Nov 20, 2025

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Stroke in Women.

Moira K Kapral1, Cheryl Bushnell2

  • 1Department of Medicine (Division of General Internal Medicine), University of Toronto, Ontario, Canada (M.K.K.).

Stroke
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PubMed
Summary
This summary is machine-generated.

Recent research shows sex and gender impact stroke care and outcomes. Understanding these differences can improve treatment, like endovascular therapy, and stroke prevention in women.

Keywords:
outcome assessment, health carepregnancysex factorsstrokewomen

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Area of Science:

  • Neurology
  • Public Health
  • Women's Health

Background:

  • Stroke epidemiology, care, and outcomes exhibit significant sex-based disparities.
  • Existing research often overlooks nuanced sex and gender influences on neurological events.
  • Understanding these differences is crucial for equitable healthcare and effective interventions.

Purpose of the Study:

  • To review recent advancements in understanding sex and gender differences in stroke.
  • To explore variations in endovascular therapy benefits based on sex.
  • To examine stroke outcomes and prevention strategies, particularly for women with specific health conditions.

Main Methods:

  • Literature review of recent studies on sex and gender in stroke.
  • Analysis of data concerning endovascular therapy efficacy across sexes.
  • Investigation of stroke prevention in women with a history of hypertensive disorders of pregnancy.

Main Results:

  • Evidence suggests sex and gender influence the benefits of endovascular stroke therapy.
  • Outcomes following stroke and transient neurological events vary between sexes.
  • Hypertensive disorders of pregnancy are linked to stroke risk in women, highlighting a potential prevention target.

Conclusions:

  • Sex and gender are critical determinants in stroke epidemiology, treatment response, and outcomes.
  • Tailoring interventions, such as endovascular therapy, based on sex may improve patient care.
  • Targeted stroke prevention strategies for women, especially those with a history of hypertensive disorders of pregnancy, are warranted.