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Updated: Nov 20, 2025

Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation
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PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness

Yi Yang1, Lili Song1, Xia Huang1

  • 1Key Laboratory of Pediatric Hematology and Oncology Ministry of Health, Department of Hematology and Oncology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.

Aging
|January 25, 2021
PubMed

Keywords:
PRPS1/2apoptosispluripotent stem cellspurine biosynthesisstemness

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