Diffuse large-cell lymphoma of the nasolacrimal sac

A 63-year-old woman was referred for consultation with a clinical picture of lacrimal sac obstruction. The presence of a noncompressible mass and patency on irrigation suggested a nasolacrimal sac tumour. At biopsy a frozen section was interpreted as being consistent with lymphoma. Examination of permanent histologic sections confirmed the diagnosis of diffuse large-cell lymphoma. Postoperatively, after complete investigation and staging, the isolated extranodal lymphoma was treated with radiation therapy. Non-Hodgkin's lymphoma limited to the lacrimal sac is rare. Its management is discussed.