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Published on: November 27, 2016
Pediatric biliary disorders: Multimodality imaging evaluation with clinicopathologic correlation
Hassan Aboughalia1, Helen Hr Kim2, Andre A S Dick3
1Radiology Department, University of Washington Medical Center, Seattle, WA 98195, United States of America.
Insights
Pediatric biliary tree pathologies differ by age, from congenital anomalies in newborns to acquired conditions in older children. Multimodality imaging is crucial for diagnosis and management of these unique pediatric biliary diseases.
Area of Science:
- Pediatric Radiology
- Gastrointestinal Imaging
- Hepatobiliary Diseases
Background:
- Biliary tree pathologies in children present uniquely compared to adults, varying with age.
- Congenital anomalies arise from in utero factors, while acquired conditions affect older children.
- Effective management necessitates understanding age-specific presentations and imaging features.
Purpose of the Study:
- To review the anatomy and embryology of the pediatric biliary system.
- To provide an overview of imaging modalities for pediatric biliary assessment.
- To discuss unique pediatric biliary pathologies, imaging findings, histopathology, and clinical management.
Main Methods:
- Review of pediatric biliary system anatomy and embryology.
- Overview of multimodality imaging techniques (e.g., ultrasound, MRI, CT).
- Discussion of pediatric-specific biliary pathologies with imaging and histopathologic correlation.
Main Results:
- Pediatric biliary pathologies exhibit age-dependent variations in presentation and consequences.
- Multimodality imaging is essential for accurate diagnosis and management planning.
- Understanding unique imaging features aids in differentiating pediatric biliary conditions.
Conclusions:
- Age-specific knowledge of pediatric biliary pathologies and their imaging characteristics is vital.
- Multimodality imaging assessment guides appropriate clinical management strategies.
- This review provides a comprehensive resource for clinicians managing pediatric biliary diseases.
Abstract:
The spectrum of pathologies affecting the biliary tree in the pediatric population varies depending on the age of presentation. While in utero insults can result in an array of anatomic variants and congenital anomalies in newborns, diverse acquired biliary pathologies are observed in older children. These acquired pathologies display different presentations and consequences than adults. Multimodality imaging assessment of the pediatric biliary system is requisite to establishing an appropriate management plan. Awareness of the imaging features of the various biliary pathologies and conveying clinically actionable information is essential to facilitate appropriate patient management. In this paper, we will illustrate the anatomy and embryology of the pediatric biliary system. Then, we will provide an overview of the imaging modalities used to assess the biliary system. Finally, we will review the unique features of the pediatric biliary pathologies, complemented by histopathologic correlation and discussions of clinical management.
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