Varicella Zoster in pregnancy
Meenu Priyadarshini Nanthakumar1, Akanksha Sood2, Maimoona Ahmed3
1Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
|January 25, 2021
Summary
Preventing chickenpox in pregnancy is crucial. Vaccination and prompt varicella zoster immunoglobulin (VZIG) for susceptible mothers protect against severe maternal and fetal complications.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Pediatrics
Background:
- Chickenpox (varicella) during pregnancy poses significant risks.
- Complications include maternal varicella pneumonia, fetal varicella syndrome, and neonatal varicella.
Purpose of the Study:
- To highlight the importance of primary and secondary prevention strategies for varicella in pregnant women.
- To emphasize the impact of interventions on fetomaternal outcomes.
Main Methods:
- Review of existing literature on varicella in pregnancy.
- Analysis of prevention strategies: vaccination and post-exposure prophylaxis.
- Evaluation of treatment outcomes for mother and neonate.
Main Results:
- Primary prevention via vaccination is a key strategy in many countries.
- Post-exposure prophylaxis with varicella zoster immunoglobulin (VZIG) is vital for susceptible pregnant women.
- Antiviral therapy and supportive care improve maternal and neonatal prognosis.
Conclusions:
- Effective prevention and timely management are essential to mitigate severe fetomaternal complications of chickenpox in pregnancy.
- Vaccination and VZIG administration are critical public health interventions.
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