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Author Spotlight: Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies
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Pathogen growth when implementing 'Time as a Public Health Control'.

Mark L Tamplin1, David A Ratkowsky1

  • 1University of Tasmania, Private Bag 98, Sandy Bay, Tasmania, 7005, Australia.

Food Microbiology
|January 26, 2021
PubMed
Summary

Time as Public Health Control (TPHC) allows food handling without refrigeration, but pathogen growth can exceed safe limits. Predictive models can improve TPHC strategies for safer food and reduced waste.

Keywords:
ComBaseFood regulationsFood safetyPredictive modelTime/temperature control

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Area of Science:

  • Food safety science
  • Microbial growth modeling
  • Public health interventions

Background:

  • Food regulatory agencies permit Time as Public Health Control (TPHC) for food handling.
  • TPHC is widely used in food service, but quantitative data on pathogen growth is limited.
  • Pathogenic bacteria can proliferate in foods under TPHC conditions.

Purpose of the Study:

  • To quantitatively assess potential pathogen growth under TPHC protocols.
  • To evaluate the adequacy of current TPHC guidelines against established microbial limits.
  • To explore the use of predictive modeling for enhancing TPHC strategies.

Main Methods:

  • Developed a worst-case pathogen growth rate model using ComBase broth data.
  • Constructed a separate worst-case growth model from ComBase database records.
  • Estimated maximum pathogen growth over 4 hours at various temperatures (5°C, 25°C, 44°C).

Main Results:

  • Estimated pathogen growth ranged from 0.006 to 6.16 log CFU within 4 hours.
  • Growth reached 3.1 log CFU at 25°C, potentially exceeding safe limits.
  • TPHC implementation may lead to pathogen growth surpassing 1- and 3-log limits.

Conclusions:

  • Predictive models can inform the development of safer TPHC criteria.
  • Improved TPHC strategies can mitigate microbial hazards in potentially hazardous foods.
  • This approach may reduce food waste and encourage temperature sensor use.